Differential diagnosis of an oral mucosal pigmented lesion: a case of essential melanosis Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Not Cancer! Understanding Dark Spots in the Mouth, Have you noticed a dark spot on your lips, gums, or inside your mouth? Dont panic! In this video, Dr. Shifali Arora explains melanotic macules a What Caused These Multiple Hyperpigmented Macules of the Mouth? Mucosal melanocytic macules This is a picosecond laser treatment of labial melanotic macules on the gingiva. Note the green flashes of the 532 nm laser as well as the immediate tissue whitening of the treated area. This