Hemolytic Anemias Part 4: G6PD Deficiency; Pathophysiology,Morphology, clinical features Response of Human Red Blood Cells to Acute and Chronic Oxidant Challenge as Observed Through the Glutathione and Glutathionyl Hemoglobin Redox Pairs In Vitro and In Vivo Glutathione production and turnover in RBC. Schematically presented are Download Scientific Diagram Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Real Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function: Stem Cell Reports Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification